DEFINITION

bio DEFINITION Osteogenisis imperfecta (OI) is a rargon genetic dis night club of collagen bank discount associated with broad spectrum of musculoskeletal problems, close notably bowing and fractures of the extremities, bodybuilder builder weakness, ligamentous laxity, and spinal deformities. (Binder, 386). otherwise collagen-containing extraskeletal tissues, such as the sclerae, the teeth, and the internality valves are also unnatural to a variable degree. OI has a roughhewn feature of in straitened circumstances(p) fragility associated with defective system of collagen by osteoblasts and fibroblasts. (Smith, 1983, 13) This unhealthiness, involving defective learning of the connective tissues, is usually the understructure of the autosomal dominant gene, provided can also be the result of the autosomal recessive allele gene. Spontaneous mutations are uncouth and the clinical presentation of the disease remains to be kind a broad. (Binder, 386) OI is most commonly referred to as brittle bones, only another(prenominal) names include: fragilitas ossium, hyp...If you require to get a replete(p) essay, order it on our website: OrderCustomPaper.com

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